Harper Woods Adrenals: Adrenals is where your adrenal glands make hormones. One of these is cortisol, which helps your body deal with stress. According to the adrenal fatigue theory, if your life is too stressful, your adrenal glands may not pump out enough hormones, leading to a wide variety of symptoms such as Adrenals are a huge part of the healing process. When you’re overly stressed, your adrenals can become extremely fatigued. Adrenal Fatigue Theory is the adrenal fatigue theory suggests that prolonged exposure to stress could drain the adrenals leading to a low cortisol state.